Leukemia
NA
Accepting Patients
nct/study# NCT03258931 / ARO-021
Phase III Randomized Study Of Crenolanib Versus Midostaurin Administered Following Induction Chemotherapy And Consolidation Therapy In Actively Diagnosed Subjects With FLT3 Mutated Acute Myeloid Leukemia
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Leukemia
Phase I
Accepting Patients
nct/study# NCT03555955 / CPX351-102
A Phase 1 Trial To Evaluate The Potential Impact Of Renal Impairment On The Pharmacokinetics And Safety Of CPX-351 (Daunorubicin And Cytarabine) Liposome For Injection Treatment In Adult Patients With Hematologic Malignancies
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Leukemia
Phase II
Active
nct/study# NA / ASTX727-07
This Is A Single-Arm, Open-Label, Multicenter, Non- Randomized Interventional Study To Evaluate The Pharmacokinetic (PK) Interaction, Safety, And Preliminary Efficacy Of ASTX727 When Given In Combination With Venetoclax For The Treatment Of Actively Diagnosed Acute Myeloid Leukemia (AML) In Adults Who Are Age 75 Years Or Older, Or Who Have Comorbidities That Preclude Use Of Intensive Induction Chemotherapy.
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Leukemia
Phase III
Accepting Patients
nct/study# NCT04472598 / M16-191
Abbvie, Protocol: M16-191, PI: Dr. Mccloskey, Title A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study Of Navitoclax In Combination With Ruxolitinib Versus Ruxolitinib In Subjects With Myelofibrosis (TRANSFORM-1)
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Leukemia
Phase III
Accepting Patients
nct/study# NCT04468984 / M20-178
Abbvie, Protocol: M20-178, PI: Dr. Mccloskey, A Randomized, Open-Label, Phase 3 Study Evaluating Efficacy And Safety Of Navitoclax In Combination With Ruxolitinib Versus Best Available Therapy In Subjects With Relapsed/Refractory Myelofibrosis (TRANSFORM-2)
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Leukemia
NA
Accepting Patients
nct/study# NCT04256317 / ASTX030-01
A Multi-Phase, Dose-Escalation Followed By An Open-Label, Randomized, Crossover Study Of Oral ASTX030 (Cedazuridine And Azacitidine Given In Combination) Versus Subcutaneous Azacitidine In Subjects With Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML), Or Acute Myeloid Leukemia (AML)
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