Leukemia
Phase I
Accepting Patients
nct/study# NCT03555955 / CPX351-102
A Phase 1 Trial To Evaluate The Potential Impact Of Renal Impairment On The Pharmacokinetics And Safety Of CPX-351 (Daunorubicin And Cytarabine) Liposome For Injection Treatment In Adult Patients With Hematologic Malignancies
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Leukemia
Phase II
Active
nct/study# NA / ASTX727-07
This Is A Single-Arm, Open-Label, Multicenter, Non- Randomized Interventional Study To Evaluate The Pharmacokinetic (PK) Interaction, Safety, And Preliminary Efficacy Of ASTX727 When Given In Combination With Venetoclax For The Treatment Of Actively Diagnosed Acute Myeloid Leukemia (AML) In Adults Who Are Age 75 Years Or Older, Or Who Have Comorbidities That Preclude Use Of Intensive Induction Chemotherapy.
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Leukemia
Phase III
Accepting Patients
nct/study# NCT04472598 / M16-191
Abbvie, Protocol: M16-191, PI: Dr. Mccloskey, Title A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study Of Navitoclax In Combination With Ruxolitinib Versus Ruxolitinib In Subjects With Myelofibrosis (TRANSFORM-1)
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Leukemia
Phase I/II
Active
nct/study# NA / APTEVO
Phase 1-2 Study Of A Bispecific CD3xCD123 Antibody In Acute Myeloid Leukemia Patients
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Leukemia
Phase III
Active
nct/study# NA / GS-US-546-5857
Phase 3 Study To Evaluate The Safety And Efficacy Of Magrolimab In Combination With Azacitidine Versus Physician’s Choice Of Venetoclax In Combination With Azacitidine Or Intensive Chemotherapy In Previously Untreated Adults With TP53 Mutant Acute Myeloid Leukemia (ENHANCE-2)
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Leukemia
Phase I/II
Active
nct/study# NA / GSK3326595
A Phase I/II Study To Investigate The Safety And Clinical Activity Of GSK3326595 And Other Agents In Subjects With Myelodyplastic Syndrome And Acute Myeloid Leukaemia
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