Skin and Soft Tissue
Phase II
Accepting Patients
nct/study# NCT04577807 / LUMINOS-102
PVSRIPO with and without Immune Checkpoint Blockade in Advanced PD-1
Refractory Melanoma
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Skin and Soft Tissue
Phase II
Accepting Patients
nct/study# NCT04768881 / XPORT-MEL-033
A PHASE 2 OPEN-LABEL MULTICENTER STUDY TO EVALUATE THE SAFETY AND EFFICACY OF SELINEXOR IN COMBINATION WITH PEMBROLIZUMAB IN ACTIVELY DIAGNOSED OR RECURRENT ADVANCED MELANOMA
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Skin and Soft Tissue
Phase III
Accepting Patients
nct/study# NCT03486873 / MK3475-587
A Multicenter, Open label, Phase III Extension Trial to Study the Long-term Safety and Efficacy in Participants with Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab Trial.
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Skin and Soft Tissue
Phase III
Accepting Patients
nct/study# NCT03833167 / MK-3475-630
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Pembrolizumab Versus Placebo as Adjuvant Therapy Following Surgery and Radiation in Participants with High-Risk Locally Advanced Cutaneous Squamous Cell Carcinoma (LA cSCCC) (KEYNOTE-630)
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Skin and Soft Tissue
Phase II
Accepting Patients
nct/study# NCT03897881 / MRNA-4157-P201
A Phase 2 Randomized Study of Adjuvant Immunotherapy With the Personalized Cancer Vaccine mRNA-4157 and Pembrolizumab Versus Pembrolizumab Alone After Complete Resection of High-Risk Melanoma (KEYNOTE- 942)
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Skin and Soft Tissue
Phase III
Accepting Patients
nct/study# NCT04410445 / 20-214-29/CA045-022
A Phase 3, Randomized, Open-label Study to Compare Adjuvant Immunotherapy of Bempegaldesleukin Combined With Nivolumab Versus Nivolumab After Complete Resection of Melanoma in Patients at High Risk for Recurrence
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